Imaging Tumor Acidity: pH-Low Insertion Peptide Probe for Optoacoustic Tomography

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Imaging Tumor Acidity: pH-Low Insertion Peptide Probe for Optoacoustic Tomography.

Optoacoustic tomography has been used for the detection of pancreatic ductal adenocarcinoma targeted by pH-low insertion peptide (pHLIP) conjugated to near-infrared fluorescent dye. It was proved that tumor targeting is pH dependent. The approach could have major implication for detection and monitoring of pancreatic and other cancers.

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ژورنال

عنوان ژورنال: Clinical Cancer Research

سال: 2015

ISSN: 1078-0432,1557-3265

DOI: 10.1158/1078-0432.ccr-15-1502